In this paper, the dynamic model of the rigid space stepped-pipe strings system is derived with Lagrangian method to represent the system dynamic behaviors which enriches the analysis method of longitudinal vibration of stepped-pipe strings.The stepped-pipe strings is constructed of pipes with different diameters and lengths, the physical propertie
Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway
Quinones can modify biological molecules through both redox-cycling reactions that yield radicals (semiquinone, superoxide and hydroxyl) and via covalent adduction to nucleophiles (e.g.thiols and amines).Kinetic data indicate that Cys residues in GSH MAGNESIUM CHELATE 125 MG and proteins are major targets.In the studies reported here, the interacti
Optimized Nanostructured Lipid Carriers Integrated into In Situ Nasal Gel for Enhancing Brain Delivery of Flibanserin
Usama A Fahmy,1 Osama AA Ahmed,1 Shaimaa M Badr-Eldin,1,2 Hibah M Face Shield Aldawsari,1 Solomon Z Okbazghi,3 Zuhier A Awan,4 Muhammed A Bakhrebah,5 Mohammad N Alomary,5 Wesam H Abdulaal,6 Carlos Medina,7 Nabil A Alhakamy1 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmaceuti
"Sleight of Hand" or "Selling Our Soul"? Surviving and Thriving as Critical Qualitative Health Researchers in a Positivist World
The commodification and corporatization of research within the academy, research institutes, and professional and political sectors has ignited much attention within the critical qualitative health field.Of particular concern is that the ascendance of neoliberal rationality is increasingly RNA making critical qualitative research transgressive and